Patterns DNA Sequences - Worksheet #10 (Splice site discovery)

Determine the consensus sequences for human splice sites.

• Human internal exons

1. 205 nucleotides
   
   GATGTTCCTGTCCTTCCCCACCACCAAGACCTACTTCCCGCACTTCGACCTGAGCCACGGCTCTGCCCAGGTTAAGGGCC ACGGCAAGAAGGTGGCCGACGCGCTGACCAACGCCGTGGCGCACGTGGACGACATGCCCAACGCGCTGTCCGCCCTGAGC GACCTGCACGCGCACAAGCTTCGGGTGGACCCGGTCAACTTCAAG

2. 168 nucleotides
   
   TGCACCCACTCTGGACGGTCCCGGTCTCCGTGCCAGGGGGCACCCGGCAGTCTCCTATTAACATCCAGTGGAGGGACAGC GTCTATGACCCCCAGCTGAAGCCACTCAGGGTCTCCTATGAAGCGGCATCCTGCCTGTACATCTGGAACACTGGCTACCT CTTCCAGG

3. 75 nucleotides
   
   GAATTAGTGGTGGGCCCTTG GAAAACCACTACAGACTGAA GCAATTTCACTTCCACTGGG GAGCAGTGAACGAGG

4. 83 nucleotides
   
   TGAAGCAATTTCACTTCCACTGGGGAGCAGTGAACGAGGGGGGCTCAGAGCACACAGTGGACGGCCACGCGTACCCCGCAGAG

• Human introns

1. 163 nucleotides
   
   GTGAGCCGTGCCCGTAACTGGCACGATGGCGCTTCATGGAAGGCGTCTCTCTTGCTTGGCAGCGTTACTAAGAATGGAGG GACCACATAAGGCCTGAGGAACACCCAGAGGCTGGCTAACCCTGCACTCATACCAAGCTCACCCTGGCTGCCCTCTATTC CAG

2. 267 nucleotides
   
   GTAAGCTGCATATTTGAAATCAGCAGGCCGGGCGCGGAGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAG GTGGATCACGTGAGGTTGGGAGTTCGAGACCAGCCTGACCAACATGGAAACCCCGTCTCACTAAAAATACTTATCTCGGG GGAAGGACTTCCTTCCAAGCACCATGAAGGCCTCACGTGCTGAGACAAGATGGAAGCTCCTAGTCTCCCGTGAGGACTGA CACGTCCTGTGCTTCTCGGTCTCTCAG

3. 845 nucleotides
   
   GTAAGAGGTTCAGAGTGGCTTTGGATTCCCAGGAACTTTGTGTCACCAGCATTCATTGGTAGTTCTGTTCCCATAGGGCA TGTTGGAAGTCACCAAGCATGTTCATCTCTGTGGCCTCATTTGCTCCTCCCAATAACCTTAAGAGGGAGGTATCATTAGC CCATTATACAGTTGAGAACACTGAGATTCAGGCTGGGTAAGCGACCCAGATGGCAGTTACTGGAGCCAGAGCTTGAACAT CAGGTCTATGAATGAACTCTGTGACCTTTGGTGGTATTGCCCAATCCTCTGAGTCTTCTGAGTTTTCATTTCCTCTTTTA TTTAAAGTCAGGGGATTGGGTTTGATGTATTTAGTGCAGTGCAGTTCAGGCTTCCCATAAGTAACTCAGGGAAGAAAATG CCTGTCAGAGAAGTTTCTTTCTTGCCAAGGGCCCATATCCACTTCTCGCCTGGCCCAAAGTTATAGCTGGCTCCTGTGAG GGACCATTTATGACCAGAGAATCCCGGGGTATGTTGTTGGCAATGAAATGCCCTGGGCCCCCAGTAGGCCTGGGAGACAG GGAGATTGGAAGAAGCCTCATTTCATCATGCCAGGCCTTTCCTGTTGCATTTTCATGCAGCTATCTAACCTGAGTAACAG GTCACAGATACACTGCACTGGAAGAAACCCTGGACTTTCCATAGTTGATCCCTAGAGCCTGCCCATAACACTCCAATGCA CATGGAGTAGCAGAGGTCTAGGATGGGTGACTTCCTCCTTCCAGAGTCAGCCCTTGTCAGCTTTAGGGAGCTCCAACAAG TGGAATGTCCTTTCTTGCAATGAAATAACTTCTTCATATCTCCAG

4. 306 nucleotides
   
   GTTTGTAGACGCGGCCTAACAGCACATATCTGCACACTTTTCATGTCTCCGGCTCTATGGCGCGGGGTGACGCGCCATTT TTTTAGTAGAGACGGGTTAACGATGTGTTAGCCAGGATGGTCTTGATCTCCTGACCTCGTGATCGACCCACCTCGGCCTC CGAAGGTGCTGGGATTACAGGTGTGAGCCACGAAGGCTGGACATTTCATTATGATTAAGTGGACACATAGGTCAGCCATT CAGAAGGGGAAGTGACTGTCTTATTTCTTGCTGATCAATTTAAGTTCTCTTTCCATTGTGTTTCAG